US firm PCI Pharma Services has signed an agreement to partner with CSP Technologies for US clinical trials and to undertake stability testing using the latter’s Activ-Blister packaging solutions.

Activ-Blister is designed to offer protection and to support speed-to-market for pharmaceutical and medical device products that are vulnerable to moisture and gases, especially oxygen.

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It controls the internal atmosphere of individual blister cavities and enables improved stability and enhanced shelf life.

Activ-Blister solutions use silica gel and molecular sieve technology to absorb moisture, oxygen and other gases. They can be tailored to accommodate any tablet or capsule.

Moreover, they can be used with various blister packaging formats, such as push-through blisters, peel/push blisters, cold-form foils and high-barrier films containing Aclar laminates.

PCI Clinical Services senior vice-president Bob Misher said: “With the pressure on pipeline development to reduce lead-times and reduce drug development costs, coupled with a growing focus on specialised medicines, our clients are challenged to get products through clinical phases and into commercialisation more quickly than ever before.

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“With CSP’s Activ-Blister solutions, the proven technology will substantially impact the success of the packaging system in achieving optimal shelf life, resulting in faster speed-to-market for our clients.”

“Often, this results in drug products that are very sensitive to moisture, oxygen or other gases and this can be problematic for both expedited clinical study, as well as in progressing to commercialisation.

“With CSP’s Activ-Blister solutions, the proven technology will substantially impact the success of the packaging system in achieving optimal shelf life, resulting in faster speed-to-market for our clients.”

CSP Technologies Business Development vice-president Craig Voellmicke noted that the collaboration will help extend shelf life and optimise overall package design.

The company is specialised in moisture protection and gas scavenging solutions, which assist in protection of sensitive products in several industries, including pharmaceuticals, drug delivery systems/medical devices, diagnostics, food, and sensitive electronic components.

PCI is engaged in outsourced drug manufacturing, clinical trial services, and commercial packaging and serves clients in the global healthcare industry.

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